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testosterone cypionate dosage

Pharmacodynamics: mucolytic tool. It has sekretomotornym, sekretoliticheskim and expectorant action; stimulates serous cells of glands of bronchial mucosa, increases the amount of mucous secretion and release of a surface-active substance (surfactant) in the alveoli and bronchi;normalizes impaired ratio of serous and mucous components of phlegm. By activating the hydrolyzing enzymes and increasing the release of lysosomes of Clara cells, reduces the viscosity of sputum. It increases motor activity of ciliated epithelium, increases mucociliary transport. Once inside the action occurs within 30 minutes and lasts for 6-12 hours.

The absorption – high, time to maximum blood concentration (TC max ) – h 2, connection with plasma proteins – 80%. Penetrates through the blood-brain barrier, placental barrier, excreted in breast milk.
Metabolism – in the liver, forms dibromantranilovuyu and glucuronic acid conjugates. . The half-life (T?) – 7-12 hours excreted by the kidneys: 90% in the form of water-soluble metabolites in unmodified form – 5%. T? Increases with severe chronic renal failure, does not change with impaired hepatic function.

Respiratory system diseases with the formation of viscous mucus: acute and chronic bronchitis, pneumonia, chronic obstructive pulmonary disease (COPD), bronchial asthma with obstruction of sputum discharge, bronchiectasis, cystic fibrosis.

Hypersensitivity, children under 6 years of age, pregnancy (I term). Precautions The drug should be used with caution in patients with gastric ulcer and duodenal ulcers, as well as in patients with renal and hepatic insufficiency.

Use during pregnancy and lactation :
The drug is not recommended for use during the I trimester of pregnancy. If necessary, the use of testosterone cypionate dosage in II-III trimesters of pregnancy and during breast-feeding should evaluate the potential benefits for the mother and the possible risk to the fetus / baby.

Dosage and administration (dose regimen)
Inside, during a meal, with a small amount of liquid. Adults and children over 12 years – 30 mg 3 times a day during the first 2-3 days, followed by 30 mg two times daily or 15 mg (half tablet) 3 times a day for children 6-12 years – 15 mg (half tablet) 2-3 times a day.
It is not recommended to use without a doctor’s appointment for more than 4-5 days.

Side effects:
Allergic reactions: skin rash, urticaria, angioedema, in some cases – allergic contact dermatitis, anaphylactic shock.
Rarely – weakness, headache, diarrhea, dry mouth and respiratory tract, rash, runny nose, constipation, dysuria. With prolonged use at high doses – gastralgia, nausea, vomiting.

Overdosing Symptoms : nausea, vomiting, diarrhea. Treatment : artificial vomiting, gastric lavage in the first 1-2 hours after taking the drug; reception of fat-containing products.

Interaction with other drugs
combined use of antitussive drugs leads to difficulty sputum discharge on the background to reduce coughing. Increases penetration in bronchial secretion of amoxicillin, cefuroxime, erythromycin testosterone cypionate dosage and doxycycline.

Specific guidance
should not be combined with antitussive drugs that prevent removal of phlegm.

Form release
tablets 30 mg. At 10, 20 or 30 tablets in blisters.
At 1, 2, or 3 blisters of 10 tablets;
2 blisters of 20 tablets or 1 strip cellular pack of 30 tablets together with instructions for use placed in a pile of cardboard. dragon pharma labs