Pharmacodynamics: antitussive and has a combined drug of plant origin bronchodilatory action. Glaucine hydrobromide suppresses the cough center, not leading, however, to respiratory depression, constipation and development cypionate testosterone of drug dependence. Ephedrine stimulates respiration, dilates the bronchi, and (due to the vasoconstrictor action) eliminates the swelling of the bronchial mucosa. Basil oil has a sedative (weak), antimicrobial and antispasmodic action.
Pharmacokinetics: At intake glaucine hydrobromide is rapidly absorbed in the gastrointestinal tract. Time to maximum concentration – about 1.5 hours. It is metabolized in the liver and excreted primarily in the urine.
Ephedrine hydrochloride is well absorbed in the gastrointestinal tract. The half-life – about 3-6 hours. Return with urine largely unchanged.
Indications for use:
Combined therapy of diseases of the respiratory system, accompanied cypionate testosterone by a dry cough: acute inflammatory diseases of the upper respiratory tract, acute and chronic bronchitis, tracheobronchitis, COPD, asthma, pneumonia, bronchiectasis, whooping cough.
Hypersensitivity to the drug, pregnancy (I term), breastfeeding, hypertension, coronary heart disease, severe organic heart disease, heart failure, pheochromocytoma, thyrotoxicosis, insomnia, angle-closure glaucoma, prostatic cypionate testosterone hypertrophy with clinical symptoms, children’s age ( up to 3 years).
Precautions – Patients with a propensity to develop drug dependence. Due to the ethanol content in the drug should use caution in patients with liver disease, alcoholism, epilepsy, brain diseases, pregnant women and children.
Dosage and administration:
For Adults: 2 measuring spoons / cups (10 ml) 3-4 times a day; Children 3-10 years – 1 measuring spoon / cup (5 ml) 3 times a day; for children over 10 years – 2 measuring spoons / cups (10 ml) 3 times a day.
Cardio-vascular system: tachycardia, arrythmia, increased blood pressure.
From the nervous system: tremor, agitation, insomnia, dizziness.
From the digestive system: nausea, vomiting, anorexia and constipation.
From endocrine system: increased libido, dysmenorrhea.
Co Urinary system: difficulty urinating, urinary retention in patients with benign prostatic hyperplasia.
Skin and mucous membranes: rash, increased sweating.
Other: visual disturbances, tachyphylaxis.
Children – drowsiness.
Symptoms: Nausea, vomiting, loss of appetite, agitation, poor circulation, limb tremor, dizziness, sweating, difficulty urinating.
Treatment: gastric lavage and symptomatic agents.
Interaction with other drugs:
Bronholitin can be used simultaneously with antibiotics, antipyretics and vitamins. Due to the presence in the composition of the drug ephedrine, it is necessary to bear in mind its drug interactions: weakens the effects of narcotic cypionate testosterone and hypnotic drugs. When applied simultaneously with cardiac glycosides, quinidine, tricyclic antidepressants increase the risk of arrhythmias. In an application with reserpine and monoamine oxidase inhibitors possible sharp rise in blood pressure, with a non-selective beta-blockers – decrease of bronchodilator action.
No data on adverse drug interactions glaucine with other drugs.
Caution should be exercised when driving and operating machines due to possible occurrence of dizziness and blurred vision.
In applying the drug should be considered that 1 measuring spoon – 5 ml contains up to 0.069 g of ethanol (96% – 1.7% vol.).
At 125 grams of the drug in a bottle of dark glass or PET bottle dark, a sealed cypionate testosterone aluminum cap to control the first opening or the plastic cap from the high pressure polyethylene bursting ring. Each bottle adhesive label paper for offset printing with appropriate labeling. Each bottle with a measuring spoon or cup, and instructions for use are placed in a stack of cardboard. steroids for sale geneza pharmaceuticals injectable steroids